Research at the National Institute of Ageing in Baltimore, Maryland has examined the idea that sporadic bouts of hunger actually cause new neurons to grow.
In a 2003 mouse study overseen by Mark Mattson, head of the National Institute on Aging's neuroscience laboratory, mice that fasted regularly were healthier than mice subjected to continuous calorie restriction; they had lower levels of insulin and glucose in their blood, for example, which signified increased sensitivity to insulin and a reduced risk of diabetes.
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| Sunday was 'treat' day |
Recently Mattson and other researchers have championed the idea that intermittent fasting probably lowers the risks of degenerative brain diseases in later life. Mattson and his colleagues have shown that periodic fasting protects neurons against various kinds of damaging stress, at least in rodents. One of his earliest studies revealed that alternate-day feeding made the rats' brains resistant to toxins that induce cellular damage akin to the kind cells endure as they age.
In follow-up rodent studies, he found that intermittent fasting protects against stroke damage, suppresses motor deficits in a mouse model of Parkinson's disease and slows cognitive decline in mice genetically engineered to mimic the symptoms of Alzheimer's.
A decidedly slender man, Mattson has long skipped breakfast and lunch except on weekends. ''It makes me more productive,'' he says. The 55-year-old researcher, who has a Ph.D. in biology but not a medical degree, has written or co-authored more than 700 articles.
In follow-up rodent studies, he found that intermittent fasting protects against stroke damage, suppresses motor deficits in a mouse model of Parkinson's disease and slows cognitive decline in mice genetically engineered to mimic the symptoms of Alzheimer's.
A decidedly slender man, Mattson has long skipped breakfast and lunch except on weekends. ''It makes me more productive,'' he says. The 55-year-old researcher, who has a Ph.D. in biology but not a medical degree, has written or co-authored more than 700 articles.
If you think about this in evolutionary terms, if your hungry, you will better increase your cognitive ability because that will give you a survival advantage - if you can remember the locations of where the food is.
It seems fasting stresses your brain matter the way exercising stresses your muscles, thus ''hunger actually makes you sharper'' (Mosley, 2012). However, while this may be true in mice, human trials would need to be done to see if it is true in us.
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''An empty stomach is not a good political adviser'' ~ Albert Einstein
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